They were assumed to be true true loversThey coupled as one in the ancient porcelainThey splashed into this fountain full of hopesThey tangoed to the splatter of the washragThey began a new verve that was to live onThe Bathing BirdsThey sat high up over the old electric polesThey must be in a forever state to hold tightThey nibble amorously from aged old clayThey stare each other far into their red heartsThey cast a spell to say you are mine nowThe Bathing BirdsThey have flown oceans all on solo flightsThey made huge pacts with soldiers unknownThey climbed mountains over burning hot lavaThey walked with the devil’s aid for a push upThey bring different ropes to ties together nowThe Bathing BirdsShare this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)
Bumgarner worked the count to 3-2 before … Click here if you’re unable to view the photo gallery on your mobile device.SAN FRANCISCO — Madison Bumgarner was not going to pitch in Bruce Bochy’s final game.But he wasn’t going to miss a chance to grab a bat and take a swing.Bumgarner appeared as a pinch-hitter in the Giants’ last regular season game against Dodgers ace Clayton Kershaw, who came out of the bullpen to face San Francisco in the bottom of the fifth inning on Sunday.
The cell is quicker than the eye of our best scientific instruments. Biochemists and biophysicists are nearing closer to watching cellular magic tricks in real time but aren’t quite there yet. They know it’s just a trick of the eye, but it sure is baffling how cellular machines pull off their most amazing feats. Think, but don’t blink:Knot Wizardry: Proteins needing a fold go into a private dressing room (05/05/2003). The most glamorous and well-equipped room, the GroEL-GroES chaperone, helps the star emerge just right. How it does this is as puzzling as watching a magician untie a Gordian knot under a kerchief. There are thousands of wrong ways a protein could fold; how does the chaperone always perform the trick correctly? Some of the bonds between domains (disulfide bridges) are a long way apart. What brings them together, and what keeps the wrong bridges from forming? Some scientists at Howard Hughes Medical Institute, writing in PNAS,1 cheated and built the chaperone with one door open so they could peek inside. They still couldn’t figure it out completely. Something in the chaperone creates conditions that favor the correct “native” fold, but also fix the mistakes before the prima donna protein emerges. Somehow they do this without any ATP energy cost. “We conclude that folding in the GroEL-GroES cavity can favor the formation of a native-like topology, here involving the proper apposition of the two domains of TG [trypsinogen, the enzyme in the experiment]; but it also involves an ATP-independent conformational ‘editing’ of locally incorrect structures produced during the dwell time in the cis cavity.”Speed Solve: Maybe you’ve watched a blindfolded man solve a Rubik’s cube in seconds and wondered how it was done. You can imagine the bewilderment of German and Swiss scientists watching a protein fold in far less time. Protein chains of hundreds of amino acids have to explore a vast space of possible folds yet arrive at the one correct fold, often in fractions of a second. These scientists, writing in PNAS,2 used lasers to try to figure out in slo-mo how this happens. As with a Rubik’s cube, there are billions of ways a protein could fold incorrectly. Parts of a nascent protein chain form loops in the process of solving the puzzle. “Exponential kinetics observed on the 10 to 100-ns time scale [ns=nanosecond, a billionth of a second] are caused by diffusional processes involving large-scale motions that allow the polypeptide chain to explore the complete conformational space,” they said. “The presence of local energy minima [e.g., loops] reduces the conformational space and accelerates the conformational search for energetically favorable local intrachain contacts.” To catch these loops, they had to look fast. “Complex kinetics of loop formation were observed on the 50- to 500-ps [picosecond] time scale,” they noted. A picosecond is a trillionth of a second. Good thing they had lasers that could flash up to a femtosecond (quadrillionth of a second), or it would all be a blur.Levitation: With a feat better than defying gravity, “Cytochrome c oxidase catalyzes most of the biological oxygen consumption on Earth, a process responsible for energy supply in aerobic organisms,” wrote a Finnish team also publishing in PNAS.3 To do this trick, the enzyme has to go against the force. Scientists like to talk in dispassionate language, but they called this enzyme “remarkable,” so they must have liked the magic act. “This remarkable membrane-bound enzyme also converts free energy from O2 reduction to an electrochemical proton gradient by functioning as a redox-linked proton pump,” they remarked about the remarkable. The way this pump works has “remained elusive,” even though most of the structure has been known. With special spectroscopic and electrometric techniques, they were able to observe the trick in real time. Abracadabra led to eureka: “The observed kinetics establish the long-sought reaction sequence of the proton pump mechanism and describe some of its thermodynamic properties.” OK, tell us. What’s the secret?The 10-microsecond electron transfer to heme [iron complex] a raises the pKa of a “pump site,” which is loaded by a proton from the inside of the membrane in 150 microseconds. This loading increases the redox potentials of both hemes a and a3, which allows electron equilibration between them at the same rate. Then, in 0.8 ms, another proton is transferred from the inside to the heme a3/CuB center, and the electron is transferred to CuB. Finally, in 2.6 ms, the preloaded proton is released from the pump site to the opposite side of the membrane.So, there. Now you know the trick. Uh, how’s that again? Actually, they only figured out part of the trick; “some important details remain unsolved,” they confessed, “e.g., the identity of the proton-accepting pump site above the hemes.” Their diagram of the enzyme looks for all the world like magician’s tightly-cupped hands, with the active site secreted within. Maybe this could be dubbed sleight-of-enzyme.In the introduction to this last paper, the authors described how the enzyme is essential to all life. It is a key player in the transfer of electrons and protons that feed the ATP synthase motors that produce ATP – the universal energy currency for all living things. Water is produced in the process that generates oxygen (in plants) and consumes it (in animals). These reactions would not occur without the machinery to drive them against the physical forces of diffusion. The scientists are converging on a mechanical description of how the pumping action works. “Each of the four electron transfer steps in the catalytic cycle of CcO [cytochrome c oxidase] constitutes one cycle of the proton pump, which is likely to occur by essentially the same mechanism each time,“ they said. “Here, we report on the internal electron transfer and charge translocation kinetics of one such cycle, which is set forth by fast photoinjection of a single electron into the oxidized enzyme.”1Eun Sun Park, Wayne A. Fenton, and Arthur L. Horwich, “Disulfide formation as a probe of folding in GroEL-GroES reveals correct formation of long-range bonds and editing of incorrect short-range ones,” Proceedings of the National Academy of Sciences USA, 10.1073/pnas.0610989104, published online before print February 5, 2007.2Fierz, Satzger et al, “Loop formation in unfolded polypeptide chains on the picoseconds to microseconds time scale,” Proceedings of the National Academy of Sciences USA, 10.1073/pnas.0611087104, published online before print February 6, 2007.3Belevich et al, “Exploring the proton pump mechanism of cytochrome c oxidase in real time,” Proceedings of the National Academy of Sciences USA, 10.1073/pnas.0608794104, published online before print February 9, 2007.We may not be able to tell how it’s done, but we all know that a stage magic trick is just an illusion. But a good trick doesn’t just happen, either. It takes a lot of intelligent design to put on a good show. Split-second timing, carefully engineered props, trained assistants, planning, and precise manipulation are all required. If and when we figure out all the cell’s tricks, it should produce even more awe than a childish belief in magic. It should produce a deeper respect for the planning and execution of a well-designed show – and a hearty round of applause. Need we say how disappointing it was for Nature to submit this Stupid Evolution Quote of the Week about the same time as this last paper appeared: “The invention of oxygenic photosynthesis was a small step for a bacterium, but a giant leap for biology and geochemistry. So when and how did cells first learn to split water to make oxygen gas?” (John F. Allen and William Martin, “Evolutionary biology: Out of thin air,” Nature 445, 610-612, 8 February 2007). Shamelessly, they continued on and on: “Biologists agree that cyanobacteria invented the art of making oxygen, but when and how this came about remain uncertain.” It appears that some childish scientists still believe in magic. We hope the growing brightness of design emerging from cell biology will not cause too much pain as it shatters their illusions. If they maintain their illusions in spite of the evidence, though – well, willful blindness is its own punishment.(Visited 14 times, 1 visits today)FacebookTwitterPinterestSave分享0
It was the first loss in four games for the Filipinos, who finished way short of duplicating silver medal finishes in the last two editions of the tournament by bombing out of the quarterfinals.Korea played with flawless precision all game and made the Filipinos look a shade of the team that humbled the Chinese, 96-87, last week.FEATURED STORIESSPORTSWATCH: Drones light up sky in final leg of SEA Games torch runSPORTSSEA Games: Philippines picks up 1st win in men’s water poloSPORTSMalditas save PH from shutoutThe Koreans advanced to take on 2013 champion Iran in the Final Four after Hamed Haddadi and Co. scored an 80-70 decision of Lebanon.Terrence Romeo provided the silver lining for the Filipinos with a 22-point effort in the second quarter, where he rallied Gilas to within eight points. Catriona Gray spends Thanksgiving by preparing meals for people with illnesses Trending Articles PLAY LIST 00:50Trending Articles00:50Trending Articles00:50Trending Articles01:37Protesters burn down Iran consulate in Najaf01:47Panelo casts doubts on Robredo’s drug war ‘discoveries’01:29Police teams find crossbows, bows in HK university01:35Panelo suggests discounted SEA Games tickets for students02:49Robredo: True leaders perform well despite having ‘uninspiring’ boss02:42PH underwater hockey team aims to make waves in SEA Games NLEX, Blackwater unveil new faces in clash Read Next LOOK: Venues for 2019 SEA Games View comments LATEST STORIES WATCH: Streetboys show off slick dance moves in Vhong Navarro’s wedding MOST READ Don’t miss out on the latest news and information. Man sworn in as lawyer by judge who sentenced him to prison as a teen 20 years ago Photo from Fiba.comSouth Korea slapped yet another loss to continental rival Gilas Pilipinas, 118-86, ending what had been a promising Fiba Asia Cup campaign by the Filipinos in Beirut.The Filipinos ran right smack into the deadliest shooting display by any country in the biennial showcase as the Koreans hit 16 triples and shot at a 67-percent clip to silence a huge stunned crowd of OFWs at Nouhad Nawfal Stadium in the game that ended early Thursday morning in Manila.ADVERTISEMENT Flags of SEA Games countries raised at Athletes Village Brace for potentially devastating typhoon approaching PH – NDRRMC SEA Games in Calabarzon safe, secure – Solcom chief UPLB exempted from SEA Games class suspension
BSP sees higher prices in November, but expects stronger peso, low rice costs to put up fight Trending Articles PLAY LIST 00:50Trending Articles00:50Trending Articles00:50Trending Articles01:37Protesters burn down Iran consulate in Najaf01:47Panelo casts doubts on Robredo’s drug war ‘discoveries’01:29Police teams find crossbows, bows in HK university01:35Panelo suggests discounted SEA Games tickets for students02:49Robredo: True leaders perform well despite having ‘uninspiring’ boss02:42PH underwater hockey team aims to make waves in SEA Games Bolado, who played for National University in college, also left behind two children.Ginebra mentor Tim Cone, the late player’s coach in Alaska, and former teammates expressed shock over the incident. Brace for potentially devastating typhoon approaching PH – NDRRMC Frontrow holds fun run to raise funds for young cancer patients Fire hits houses in Mandaluyong City The 6-foot-6 Bolado, drafted 13th overall by Alaska Milk in 1994, won 11 PBA championships, including a Grand Slam with Alaska in 1996.He also suited up for Ginebra, Purefoods, Pop Cola/Coca-Cola, San Miguel and Red Bull before retiring in 2013 with career averages of 2.4 points and 2.1 rebounds.FEATURED STORIESSPORTSWATCH: Drones light up sky in final leg of SEA Games torch runSPORTSSEA Games: Philippines picks up 1st win in men’s water poloSPORTSMalditas save PH from shutoutAccording to reports, Bolado was working as a basketball coach in an international school in the Cambodian capital.He was likewise managing a Filipino restaurant with partner Anne Christine Waje at the time of his death. Don’t miss out on the latest news and information. LATEST STORIES E.T. returns to earth, reunites with grown-up Elliott in new ad Bombers, Generals clash MOST READ Photo from Cris Bolado’s Facebook accountFormer Philippine Basketball Association player Cris Bolado was killed Sunday in a motorcycle crash in Phnom Pehn, Cambodia.He would have turned 48 in October.ADVERTISEMENT LOOK: Loisa Andalio, Ronnie Alonte unwind in Amanpulo for 3rd anniversary Nonong Araneta re-elected as PFF president Kammuri turning to super typhoon less likely but possible — Pagasa Read Next View comments
Ohio State basketball is betting on the fact spectators will be seeing a lot of the Hills this season. No, not the brain-numbing, MTV reality show featuring Lauren Conrad and her catty band, but rather the sibling duo of P.J. Hill, a guard on the men’s basketball team, and his sister Tayler, a newcomer to the OSU women’s basketball team.There are undeniable similarities between the two. Both play guard and took the number four for their jerseys.P.J. Hill has long been a favorite of Buckeye fans. The 6-feet 1 inches guard has made a name for himself by coming off the bench and instantly raising the team’s intensity level with a key steal or assist. This year, Hill is being counted on this season to expand his role.“Last year, a lot of teams got away with not guarding me,” he said. “I took that personally, like ‘you can’t shoot, you’re not effective on offense, you’re not a threat.’ So I took that stuff personally. When I get in the games, I’m going to step up and knock those shots down with confidence. I’m going to be an impact player. I’m going to be a threat on both ends of the court.”While senior Hill enters the final act of his career with the OSU men’s basketball team, freshman Tayler Hill begins hers with the women’s team.Tayler Hill comes to the Buckeyes as one of the most decorated players in Minnesota basketball history. She is Minnesota’s all-time leading scorer in high school basketball, boys and girls, and was selected as a 2009 McDonald’s All American. While leading her team to a state high school championship, she averaged 31.4 points, 7.6 rebounds and 5.7 steals per game. She finished her high school playing career with 3,894 points. She joins a deep, veteran women’s basketball team that has already established leadership. “If Coach [Jim] Foster wants me on the floor, that’s where I’m going to be at,” Hill said. “If he needs me on the bench cheering my team on, then that’s what I’m going to do.”Rather than be daunted by the prospect of becoming another cog in the machine, as opposed to its centerpiece, she is embracing the positives that come with it.“I’m excited,” she said. “There were times when games got tough in high school when I had to have the ball in my hands at all times. I can rely on other players on this team, I can pass and screen away.”The pride Tayler has for her older brother shines through when she speaks of him. His non-traditional path to the OSU basketball team, which saw him transfer before his sophomore year from tiny Midland College, is a lesson to her in persistence.“My brother is my role model,” she said. “Seeing him work every day and keeping the faith that he has, I know that if he can do it, than I can too. If it wasn’t for him, I wouldn’t be where I am right now.”There’s a double meaning in that statement. Although the particulars of P.J.’s role in helping bring Tayler to OSU are unclear, his influence is not.“He was a big factor in this because my brother and I are best friends,” Tayler said. “Knowing I can count on him when things get hard was a really big deal for me.”Foster was guarded in his praise of Tayler Hill. “She’s talented and she can go up and down the floor,” Foster said. “When you’ve scored 4,000 points in your high school career, how many times have you been on the floor with players better than you?”But her freshman status does not necessarily exclude her from cracking the starting lineup in her first year, as evidenced by the playing time given to Jantel Lavender and Sammy Prahalis in their freshmen campaigns.“If you’re a great player or have the potential to be a great player, room is made for them because they earn it,” Foster said. “We’ll find out.”When asked about P.J.’s role in recruiting Tayler to OSU, Foster was glib.“I would say that he’s not disappointed that his sister’s here,” he said.Junior center Jantel Lavender, the team’s leader on the floor, likes what she sees in Tayler.“She’s a great shooter, she’s a great passer, she’s a great leader and she works extremely hard all the time,” Lavender said of Hill. “Those are the attributes that you need.”
Cody Cousino / For The LanternThen-junior Corey Brown avoids the defense during a game against Michigan on Nov. 24, 2012 at Ohio Stadium. OSU won, 26-21.Prior to coming to Ohio State, Urban Meyer’s teams had at least one thing in common: a healthy pass offense.It is an area that Meyer is looking to improve on in his second season at OSU, and he is counting on the wide receivers to grow and develop this fall into a group that could be similar to what he had when he was the coach of the Florida Gators.While Meyer was at Florida, the Gators only had one season where they averaged less than 213 yards per game through the air, a total that in his first season at Ohio State the Buckeyes fell far short of.During their undefeated season, OSU failed to reach the 200 yard mark through the air in all but four games, including only throwing for 97 yards during a 21-14 overtime victory at Wisconsin Nov. 17.Part of the problem with the Buckeyes’ passing game last year was the receiving corps, which only had two players who racked up more than 300 receiving yards. But with another year under their belts, along with an influx of young talent from Meyer’s second recruiting class, the OSU wide receivers are looking to make a big difference in the offense this season.Wide receivers coach Zach Smith said the receivers were weak last year, but in the offseason they have grown to become threats in the offense.“They’ve had trials, tribulations, had hard times, had great successes and so they have grown and learned from mistakes to the point where now they’re able to be a mature group and able to use those learning points in the past to make sure they don’t happen again and grow from them,” Smith said. “I’m pleased with the growth from them in the last year.”Junior quarterback Braxton Miller hinted that he’s looking to spread the ball around more this year, with his top two receivers senior Corey “Philly” Brown and junior Devin Smith returning this season.“We did less throwing last year, and there is going to be a lot of throwing this year,” Miller said.Brown, who led the team with 669 yards and 60 catches in 2012, is expecting a big jump in the team’s offensive production.“I think this year you can expect our offense to shoot up the charts if we keep doing what we are doing and try to eliminate the stupid mistakes, we could be one of the top offenses in the country,” Brown said.A lot of talk from fall camp surrounds junior Evan Spencer and his development into a potential star receiver.“What (Spencer has) shown flashes of at times, he’s really done consistently,” Zach Smith said. “He’s probably the one receiver that I’m most pleased with the step he’s took. That’s not to take away from Philly or Devin or guys that have taken steps. Evan has really taken a bigger step.”Offensive coordinator and quarterbacks coach Tom Herman made it clear Spencer is a starter and the rest of the receivers have also improved this fall.“The first thing that I’ve said earlier in camp was that our veterans are improved,” Herman said. “They’re better. Evan Spencer’s had a great camp. Evan Spencer’s a starting wide receiver at The Ohio State University. Philly Brown is better, Devin Smith is better. We’re better.”At OSU Media Day Aug. 11, Meyer said the top three receivers on the team were Devin Smith, Brown and Spencer, but that Spencer was having a great camp.An issue Spencer said he had last year was with hitting his routes and winning balls in the air, but has become much more confident as a player heading into the 2013 season.“Myself personally, I feel like I’m developing a little more as a route runner,” Spencer said Aug. 10. “That was my main thing this year that I was focusing on, making sure I am lowering out of my cuts, making sure every time the ball is up in the air I’m going up and getting it.”Spencer said he has taken on more of a leadership role this offseason, trying to get some of the younger players to feel more comfortable in the offense.“As an older guy, I take it upon myself to make sure that they know what they’re doing,” Spencer said. “I try to pride myself and make sure that they know what they’re doing all the time so they can go 100 percent.”Known as a big play receiver last year when he averaged 20.6 yards per catch, Devin Smith is hoping to have a big year with Miller throwing him the ball.“We talked all summer, trained all summer, we know where he’s going to place the ball, how I’m going to run my route and things like that,” Smith said about his relationship with Miller. “So it’s all about timing and we certainly got that down.”Spencer likes what he sees out of his fellow receivers, and said the offense is starting to come together.“Devin is running great routes with good speed and getting hands off, and Philly (is) explosive as always,” Spencer said. “It’s just good to see it’s all coming along.”Zach Smith is looking for his guys to have a big year, and help Miller improve on the weak passing numbers from last season.“Every guy that we’re counting on, every guy that we think is gonna be a contributing factor in our offense is capable and has shown the capability to be a dominate player,” Zach Smith said. “At least a good, functional player. We just need to see that consistently from every rep from every guy that we’re counting on.”
Jose Mourinho revealed how difficult it was for him and the players when his sacking rumors went viral before playing vs Newcastle.With the match against Chelsea fast approaching, Jose Mourinho has been making the rounds with the media and spoke about the sacking rumors that became public right before Manchester United’s match vs Newcastle.The Red Devils had to win that match with all that pressure of possibly knowing that their manager would get the boot, even he seemed on edge after the match and came out to the press conference guns blazing and crying out ‘manhunt’.All of this was justified because of how bad the relationship between Jose and certain members of the press has turned, the Portuguese manager confessed that this episode really affected him and the players before that game.Now that a little time has passed, Mourinho is wary of what will happen next as his players are getting ready for an even more difficult match at Stamford Bridge against his former Chelsea squad.Jose tries to think about the consequences of this moment as little as possible, instead, he tries to take out the positive and look forward to the next target without forgetting this behavior from a certain part of the more sensationalist members of the press.We won’t name any publications because they know who they are, the ones who are still campaigning for Jose Mourinho to get sacked.”Yes it bothers me, because I am a man like you are.”Jose Mourinho opens up to the abuse he has received in an exclusive interview with Sky Sports.Read: https://t.co/YA9Xp50prk pic.twitter.com/534xcc0Mx3— Sky Sports Premier League (@SkySportsPL) October 19, 2018Looking at the whole scenario for this Saturday’s match, that part of the press is already patiently waiting for whatever happens after the match against Chelsea.Mourinho himself revealed that he won’t celebrate too hard if he defeats his former club, but getting to defeat Maurizio Sarri’s innovative style of football will prove to be the greatest challenge that Mourinho has faced thus far during the current Premier League season.The manager knows that the noise about his possible dismissal will never stop, but he feels more prepared for it now after the terrible experience from before and after the match against Newcastle.When asked about how the players live with that constant noise, Mourinho said: “I keep telling them that it is my problem to cope with it – because I am the man – and let them enjoy their football like they did against Newcastle in the second half,” said Mourinho to Sky Sports.“I am not happy, I am honestly not happy but if somebody has to be the man then I prefer it to be me.”Daniel Farke, From mid-table in the Championship to the Premier League Manuel R. Medina – September 14, 2019 Norwich City manager, Daniel Farke, has taken his team from the middle of the table in the English Championship to play with the big boys in the Premier League.“Yes it bothers me. Because I am a man like you are. My players care.”“That weekend we did not stay at the hotel, everyone stayed at their own house and when the players woke up, from what they read on social media and on their phones, the pre-match was not easy for them.”🆕 MOURINHO EXCLUSIVE 🆕Manchester United manager Jose Mourinho says recent criticism of him and his players has hurt.Read our exclusive interview here: https://t.co/zceOTYY1ry pic.twitter.com/JcZw7RLNAx— Sky Sports Premier League (@SkySportsPL) October 19, 2018Even manager Maurizio Sarri agrees that the press has been too harsh on Jose Mourinho this early in the season, he also exposed certain members of the media for not letting the Portuguese manager work and wants this match to not have that same pressure.But knowing how the English newspapers love creating havoc, it’s nearly impossible to imagine a scenario in which Jose Mourinho won’t be at the very center of criticism regardless of the result on Saturday at Stamford Bridge.Sometimes we (the press) forget that the people we write about are also humans and talking about a manager’s good or bad work is one thing, but flat out asking for him getting sacked is a completely different situation that is not right.Jose Mourinho is one of the most successful managers in modern football, he is right to demand a little more respect from the press but we are not sure if he will withstand all this bad blood against him.I’ve even said that the man needs a break from all this, regroup and come back stronger than ever. But knowing Jose, he would rather die standing up than fleeing from any kind of confrontation with anyone who opposes [email protected] have not won in their last 8 visits to Stamford Bridge, losing 7 with Jose Mourinho losing all 3 visits with @[email protected] are 4 points better off than at this stage of their last title-winning season of 2016-17Live on Saturday on Sky Sports PL from 11:30am pic.twitter.com/nGvnL0amtn— Sky Sports Statto (@SkySportsStatto) October 19, 2018What do you think about the press pushing for Jose Mourinho to get sacked in recent months? Please share your opinion in the comment section down below.
We will tell you the reasons Ivan Rakitic needs to be sold by FC Barcelona next summer, it appears that his time at the Catalan club has passed.Even though Croatian midfielder Ivan Rakitic is still one of FC Barcelona’s top players, we truly believe that the club needs to sell him next summer and we are going to discuss the reasons we think this is the best option for both parts.The Croatian midfielder is arguably one of his country’s most decorated players alongside Luka Modric, he was an essential part of the National Team that reached a historic World Cup final last summer that they lost against France in Russia.At club level, Ivan Rakitic has practically never stopped winning and growing as a football professional. After starting with Swiss club FC Basel, a young Rakitic was scouted by German side Schalke 04 and they could buy him for €5 million back in 2007.During his time in the Bundesliga, the Croatian midfielder quickly started developing the skills that eventually took him to the Spanish La Liga after Sevilla decided to pay a low €2.5 million to the German club and that’s when his career really started to take off.Ivan Rakitic came to Spain for a long time, and it’s been 9 years already since the first time he arrived.”Sería un gran sueño para mí poder volver a jugar con la camiseta del #SevillaFC”, dijo hace menos de un año un Ivan Rakitic al que ahora, tras llegar Frenkie de Jong, empiezan a ver en la Ciudad Condal fuera del Barça https://t.co/vNu2MesTBi— Carlos Pérez (@carlosperezED) January 25, 2019With the Andalusian club, Ivan Rakitic’s football really started to flourish and his last year with them was the perfect season that called the attention of major clubs like Real Madrid, Chelsea, Manchester United, and FC Barcelona.With Cesc Fabregas leaving the Catalan club after a failed attempt to succeed there, Barcelona’s number ‘4’ jersey was suddenly open and the Spanish giants were the ones who made the biggest offer for the player.They paid a reported €21 million in 2014, he came alongside Luis Suarez on the same season and he made an immediate impact. Since then, Ivan Rakitic has completely taken charge of the position as one of the most creative midfielders in the club.Since he came to the Catalan club, Rakitic has contributed to the club’s success and won a total of 12 trophies which include three La Liga titles, one Champions League, four Copa del Rey titles, two Spanish Supercups, one UEFA Supercup, and one FIFA Club World Cup.But the new generations are coming and Ivan Rakitic has already won everything at Barcelona, it is time for him to leave room for other great players and also attempt to leave a good amount of money for his transfer to the club that gave him everything.Match Preview: Barcelona vs Valencia Boro Tanchev – September 14, 2019 Is derby time in La Liga, as Barcelona welcomes Valencia to the Camp Nou Stadium tonight at 21:00 (CET).Con la llegada de nuevos fichajes, canteras y malos partidos de Rakitic. ¿Debería el Barça venderlo y confiar en los jóvenes? pic.twitter.com/LDxEAT3CAP— Soydelbarca_ (@Soydelbarca2) January 25, 2019Even though he is already considered a veteran, Ivan Rakitic still has several good years of great football on his boots and the Catalan club should get a good deal for a World Cup runner-up who has won everything at Barcelona.Frenkie de Jong’s arrival is another reason why he needs to leave, his presence could easily prevent the Dutch young player to grow to become the player that everybody imagines he will transform into someday.The number ‘4’ that Ivan Rakitic wears right now is one that fits Frenkie perfectly, a mythical number at FC Barcelona that not any player can wear and seems destined to belong to De Jong once he comes to the club next summer.All the signs point to Ivan Rakitic leaving FC Barcelona, the only problem here is that manager Ernesto Valverde would oppose his arrival but the club already thinks that even the manager could leave soon if the results don’t come his way throughout the current season.We all know that the main target this season is the Champions League, Valverde will surely resign if he doesn’t win the title and this will leave the open door for players like Rakitic next summer.The player already told Estadio Deportivo that his dream is to return to Sevilla.We keep going 💪⚽️! ➕3️⃣✅ #ForçaBarça 🔵🔴 pic.twitter.com/xXXS8S84wY— Ivan Rakitic (@ivanrakitic) January 20, 2019Which club do you think could be better for Ivan Rakitic after FC Barcelona? Please share your opinion in the comment section down below.